Expansion of the genetic code through reassignment of redundant sense codons using fully modified tRNA

Breaking codon degeneracy for the introduction of non-canonical amino acids offers many opportunities in synthetic biology. Yet, despite the existence of 64 codons, the code has only been expanded to 25 amino acids in vitro. A limiting factor could be the over-reliance on synthetic tRNAs which lack...

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Detalles Bibliográficos
Autores principales: McFeely, Clinton A L, Dods, Kara K, Patel, Shivam S, Hartman, Matthew C T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638912/
https://www.ncbi.nlm.nih.gov/pubmed/36300637
http://dx.doi.org/10.1093/nar/gkac846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638912/
https://www.ncbi.nlm.nih.gov/pubmed/36300637
http://dx.doi.org/10.1093/nar/gkac846

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