Catastrophic chromosome fragmentation probes the nucleoid structure and dynamics in Escherichia coli

Escherichia coli cells treated with a combination of cyanide (CN) and hydrogen peroxide (HP) succumb to catastrophic chromosome fragmentation (CCF), detectable in pulsed-field gels as >100 double-strand breaks per genome equivalent. Here we show that CN + HP-induced double-strand breaks are indep...

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Detalles Bibliográficos
Autores principales: Mahaseth, Tulip, Kuzminov, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638926/
https://www.ncbi.nlm.nih.gov/pubmed/36243965
http://dx.doi.org/10.1093/nar/gkac865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638926/
https://www.ncbi.nlm.nih.gov/pubmed/36243965
http://dx.doi.org/10.1093/nar/gkac865

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