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Catastrophic chromosome fragmentation probes the nucleoid structure and dynamics in Escherichia coli
Escherichia coli cells treated with a combination of cyanide (CN) and hydrogen peroxide (HP) succumb to catastrophic chromosome fragmentation (CCF), detectable in pulsed-field gels as >100 double-strand breaks per genome equivalent. Here we show that CN + HP-induced double-strand breaks are indep...
Autores principales: | Mahaseth, Tulip, Kuzminov, Andrei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638926/ https://www.ncbi.nlm.nih.gov/pubmed/36243965 http://dx.doi.org/10.1093/nar/gkac865 |
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