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Evaluating data integrity in ribosome footprinting datasets through modelled polysome profiles

The assessment of transcriptome-wide ribosome binding to mRNAs is useful for studying the dynamic regulation of protein synthesis. Two methods frequently applied in eukaryotic cells that operate at different levels of resolution are polysome profiling, which reveals the distribution of ribosome load...

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Detalles Bibliográficos
Autores principales: Hedayioglu, Fabio, Mead, Emma J, O'Connor, Patrick B F, Skiotys, Matas, Sansom, Owen J, Mallucci, Giovanna R, Willis, Anne E, Baranov, Pavel V, Smales, C Mark, von der Haar, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638929/
https://www.ncbi.nlm.nih.gov/pubmed/35979952
http://dx.doi.org/10.1093/nar/gkac705