A guard protein mediated quality control mechanism monitors 5’-capping of pre-mRNAs

Efficient gene expression requires properly matured mRNAs for functional transcript translation. Several factors including the guard proteins monitor maturation and act as nuclear retention factors for unprocessed pre-mRNAs. Here we show that the guard protein Npl3 monitors 5’-capping. In its absenc...

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Detalles Bibliográficos
Autores principales: Klama, Sandra, Hirsch, Anna G, Schneider, Ulla M, Zander, Gesa, Seel, Anika, Krebber, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638935/
https://www.ncbi.nlm.nih.gov/pubmed/36305816
http://dx.doi.org/10.1093/nar/gkac952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638935/
https://www.ncbi.nlm.nih.gov/pubmed/36305816
http://dx.doi.org/10.1093/nar/gkac952

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