Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing

8-Oxoguanine (GO) is a major purine oxidation product in DNA. Because of its highly mutagenic properties, GO absolutely must be eliminated from DNA. To do this, aerobic and anaerobic organisms from the three kingdoms of life have evolved repair mechanisms to prevent its deleterious effect on genetic...

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Detalles Bibliográficos
Autores principales: Franck, Coste, Stéphane, Goffinont, Julien, Cros, Virginie, Gaudon, Martine, Guérin, Norbert, Garnier, Fabrice, Confalonieri, Didier, Flament, Josef, Suskiewicz Marcin, Bertrand, Castaing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638937/
https://www.ncbi.nlm.nih.gov/pubmed/36300625
http://dx.doi.org/10.1093/nar/gkac932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638937/
https://www.ncbi.nlm.nih.gov/pubmed/36300625
http://dx.doi.org/10.1093/nar/gkac932

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