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Vitamin C enhances NF-κB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells

Dendritic cells (DCs), the most potent antigen-presenting cells, are necessary for effective activation of naïve T cells. DCs’ immunological properties are modulated in response to various stimuli. Active DNA demethylation is crucial for DC differentiation and function. Vitamin C, a known cofactor o...

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Detalles Bibliográficos
Autores principales: Morante-Palacios, Octavio, Godoy-Tena, Gerard, Calafell-Segura, Josep, Ciudad, Laura, Martínez-Cáceres, Eva M, Sardina, José Luis, Ballestar, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638940/
https://www.ncbi.nlm.nih.gov/pubmed/36305821
http://dx.doi.org/10.1093/nar/gkac941