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Vitamin C enhances NF-κB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells

Dendritic cells (DCs), the most potent antigen-presenting cells, are necessary for effective activation of naïve T cells. DCs’ immunological properties are modulated in response to various stimuli. Active DNA demethylation is crucial for DC differentiation and function. Vitamin C, a known cofactor o...

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Detalles Bibliográficos
Autores principales:	Morante-Palacios, Octavio, Godoy-Tena, Gerard, Calafell-Segura, Josep, Ciudad, Laura, Martínez-Cáceres, Eva M, Sardina, José Luis, Ballestar, Esteban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638940/ https://www.ncbi.nlm.nih.gov/pubmed/36305821 http://dx.doi.org/10.1093/nar/gkac941

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