Cargando…

Vitamin C enhances NF-κB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells

Dendritic cells (DCs), the most potent antigen-presenting cells, are necessary for effective activation of naïve T cells. DCs’ immunological properties are modulated in response to various stimuli. Active DNA demethylation is crucial for DC differentiation and function. Vitamin C, a known cofactor o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morante-Palacios, Octavio, Godoy-Tena, Gerard, Calafell-Segura, Josep, Ciudad, Laura, Martínez-Cáceres, Eva M, Sardina, José Luis, Ballestar, Esteban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638940/ https://www.ncbi.nlm.nih.gov/pubmed/36305821 http://dx.doi.org/10.1093/nar/gkac941

Ejemplares similares

Coordinated glucocorticoid receptor and MAFB action induces tolerogenesis and epigenome remodeling in dendritic cells
por: Morante-Palacios, Octavio, et al.
Publicado: (2021)

SIRT1/2 orchestrate acquisition of DNA methylation and loss of histone H3 activating marks to prevent premature activation of inflammatory genes in macrophages
por: Li, Tianlu, et al.
Publicado: (2020)

Epstein–Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation
por: Hernando, Henar, et al.
Publicado: (2014)

Pre-B cell to macrophage transdifferentiation without significant promoter DNA methylation changes
por: Rodríguez-Ubreva, Javier, et al.
Publicado: (2012)

The comprehensive epigenome map of piRNA clusters
por: Kawaoka, Shinpei, et al.
Publicado: (2013)

RTEL1 is required for silencing and epigenome stability
por: Olivier, Margaux, et al.
Publicado: (2023)

High-throughput sequence-based epigenomic analysis of Alu repeats in human cerebellum
por: Xie, Hehuang, et al.
Publicado: (2009)

DNA methylation in human epigenomes depends on local topology of CpG sites
por: Lövkvist, Cecilia, et al.
Publicado: (2016)

Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF
por: Seuter, Sabine, et al.
Publicado: (2016)

Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines
por: Suzuki, Ayako, et al.
Publicado: (2014)

Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells
por: Mlambo, Tafadzwa, et al.
Publicado: (2018)

Genome-wide investigation of the dynamic changes of epigenome modifications after global DNA methylation editing
por: Broche, Julian, et al.
Publicado: (2020)

Transcriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration site
por: Šenigl, Filip, et al.
Publicado: (2012)

Integrated 3D genome, epigenome and transcriptome analyses reveal transcriptional coordination of circadian rhythm in rice
por: Zhang, Ying, et al.
Publicado: (2023)

The splicing landscape is globally reprogrammed during male meiosis
por: Schmid, Ralf, et al.
Publicado: (2013)

TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells
por: Garcia-Gomez, Antonio, et al.
Publicado: (2017)

dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression
por: O’Geen, Henriette, et al.
Publicado: (2017)

Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain
por: Kojima, Shin, et al.
Publicado: (2022)

Mitochondrial stress induces AREG expression and epigenomic remodeling through c-JUN and YAP-mediated enhancer activation
por: Hino, Yuko, et al.
Publicado: (2022)

DBC1 is a key positive regulator of enhancer epigenomic writers KMT2D and p300
por: Kim, Hwa Jin, et al.
Publicado: (2022)

Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction
por: Català-Moll, Francesc, et al.
Publicado: (2021)

SOX9 reprograms endothelial cells by altering the chromatin landscape
por: Fuglerud, Bettina M, et al.
Publicado: (2022)

SETDB1 fuels the lung cancer phenotype by modulating epigenome, 3D genome organization and chromatin mechanical properties
por: Zakharova, Vlada V, et al.
Publicado: (2022)

LSD1 mediates metabolic reprogramming by glucocorticoids during myogenic differentiation
por: Anan, Kotaro, et al.
Publicado: (2018)

Evolutionary re-wiring of p63 and the epigenomic regulatory landscape in keratinocytes and its potential implications on species-specific gene expression and phenotypes
por: Sethi, Isha, et al.
Publicado: (2017)

Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis
por: Lee, Ying-Ying, et al.
Publicado: (2018)

RNAi pathways repress reprogramming of C. elegans germ cells during heat stress
por: Rogers, Alicia K, et al.
Publicado: (2020)

Forkhead box protein D2 suppresses colorectal cancer by reprogramming enhancer interactions
por: Kim, Hyo-Min, et al.
Publicado: (2023)

NF-κB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas
por: Vento-Tormo, Roser, et al.
Publicado: (2014)

Single-cell transcriptome analysis of Physcomitrella leaf cells during reprogramming using microcapillary manipulation
por: Kubo, Minoru, et al.
Publicado: (2019)

A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress
por: Viéitez, Cristina, et al.
Publicado: (2020)

Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3 and Ezh2-dCas9 + DNMT3 hit-and-run epigenome editing
por: O’Geen, Henriette, et al.
Publicado: (2022)

Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression
por: Gordon, Katrina, et al.
Publicado: (2014)

Salicylic acid-induced transcriptional reprogramming by the HAC–NPR1–TGA histone acetyltransferase complex in Arabidopsis
por: Jin, Hongshi, et al.
Publicado: (2018)

EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma
por: Showpnil, Iftekhar A, et al.
Publicado: (2022)

The Epstein–Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins
por: Coppotelli, Giuseppe, et al.
Publicado: (2013)

H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis
por: Li, Zhiming, et al.
Publicado: (2022)

DeSUMOylation of chromatin-bound proteins limits the rapid transcriptional reprogramming induced by daunorubicin in acute myeloid leukemias
por: Boulanger, Mathias, et al.
Publicado: (2023)

MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis
por: Santolini, Marc, et al.
Publicado: (2016)

The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress
por: Lemaitre, Florence, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2ldb0hhmr2f76utilgd9qcjpbv