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Two type I topoisomerases maintain DNA topology in human mitochondria

Genetic processes require the activity of multiple topoisomerases, essential enzymes that remove topological tension and intermolecular linkages in DNA. We have investigated the subcellular localisation and activity of the six human topoisomerases with a view to understanding the topological mainten...

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Detalles Bibliográficos
Autores principales: Menger, Katja E, Chapman, James, Díaz-Maldonado, Héctor, Khazeem, Mushtaq M, Deen, Dasha, Erdinc, Direnis, Casement, John W, Di Leo, Valeria, Pyle, Angela, Rodríguez-Luis, Alejandro, Cowell, Ian G, Falkenberg, Maria, Austin, Caroline A, Nicholls, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638942/
https://www.ncbi.nlm.nih.gov/pubmed/36215039
http://dx.doi.org/10.1093/nar/gkac857