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Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes

HflX is a ubiquitous bacterial GTPase that splits and recycles stressed ribosomes. In addition to HflX, Listeria monocytogenes contains a second HflX homolog, HflXr. Unlike HflX, HflXr confers resistance to macrolide and lincosamide antibiotics by an experimentally unexplored mechanism. Here, we hav...

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Detalles Bibliográficos
Autores principales: Koller, Timm O, Turnbull, Kathryn J, Vaitkevicius, Karolis, Crowe-McAuliffe, Caillan, Roghanian, Mohammad, Bulvas, Ondřej, Nakamoto, Jose A, Kurata, Tatsuaki, Julius, Christina, Atkinson, Gemma C, Johansson, Jörgen, Hauryliuk, Vasili, Wilson, Daniel N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638945/
https://www.ncbi.nlm.nih.gov/pubmed/36300626
http://dx.doi.org/10.1093/nar/gkac934