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CGP42112: the full AT(2) receptor agonist and its role in the renin–angiotensin–aldosterone system: no longer misunderstood

For years, the AT(2)R-selective ligand CGP42112 has been erroneously characterized as a partial agonist, partly due to its ability to also interact with the AT(1)R at high concentrations. As late as 2009, it was still being characterized as an antagonist as well. In this perspective/opinion piece, w...

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Detalles Bibliográficos
Autores principales:	Restrepo, Yazmin M., Noto, Natalia M., Speth, Robert C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2022
Materias:	Cardiovascular System & Vascular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638965/ https://www.ncbi.nlm.nih.gov/pubmed/36326719 http://dx.doi.org/10.1042/CS20220261

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