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CGP42112: the full AT(2) receptor agonist and its role in the renin–angiotensin–aldosterone system: no longer misunderstood
For years, the AT(2)R-selective ligand CGP42112 has been erroneously characterized as a partial agonist, partly due to its ability to also interact with the AT(1)R at high concentrations. As late as 2009, it was still being characterized as an antagonist as well. In this perspective/opinion piece, w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638965/ https://www.ncbi.nlm.nih.gov/pubmed/36326719 http://dx.doi.org/10.1042/CS20220261 |