Three-Component Synthesis of Pyridylacetic Acid Derivatives by Arylation/Decarboxylative Substitution of Meldrum’s Acids

[Image: see text] A convenient and simple three-component synthesis of substituted pyridylacetic acid derivatives is reported. The approach centers on the dual reactivity of Meldrum’s acid derivatives, initially as nucleophiles to perform substitution on activated pyridine-N-oxides, then as electrop...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Tarn C., Marsden, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638998/
https://www.ncbi.nlm.nih.gov/pubmed/36257810
http://dx.doi.org/10.1021/acs.joc.2c01597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638998/
https://www.ncbi.nlm.nih.gov/pubmed/36257810
http://dx.doi.org/10.1021/acs.joc.2c01597

Ejemplares similares