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NOD2‐mediated HDAC6/NF‐κb signalling pathway regulates ferroptosis induced by extracellular histone H3 in acute liver failure

Acute liver failure (ALF) is life‐threatening and often associated with high mortality rates. The aim of the present study was to investigate whether extracellular histone H3 could induce ferroptosis in hepatic macrophages in ALF and explore its potential mechanism. RAW264.7 macrophages and C57BL/6...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Zhang, Qingqi, Cao, Pan, Shi, Chunxia, Zhang, Luyi, Wang, Luwen, Gong, Zuojiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639038/
https://www.ncbi.nlm.nih.gov/pubmed/36226351
http://dx.doi.org/10.1111/jcmm.17582