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Mitochondrial derived peptide MOTS‐c prevents the development of heart failure under pressure overload conditions in mice

MOTS‐c, a mitochondrial‐derived peptide (MDP), has been shown to have multiple biological activities such as antioxidation, anti‐inflammation, and anti‐apoptosis properties. In the present study, we aimed at evaluating the therapeutic effect of MOTS‐c peptide in an animal model of heart failure. The...

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Detalles Bibliográficos
Autores principales: Zhong, Peng, Peng, Jianye, Hu, Yewen, Zhang, Jun, Shen, Caijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639045/
https://www.ncbi.nlm.nih.gov/pubmed/36156853
http://dx.doi.org/10.1111/jcmm.17551