Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine

[Image: see text] Chemo- and diastereoselective 1,4-conjugate additions of anionic and radical C-nucleophiles to a chiral bicyclic dehydroalanine (Dha) are described. Of particular importance, radical carbon photolysis by a catalytic photoredox process using a simple method with a metal-free photoca...

Descripción completa

Detalles Bibliográficos
Autores principales: Oroz, Paula, Navo, Claudio D., Avenoza, Alberto, Busto, Jesús H., Corzana, Francisco, Jiménez-Osés, Gonzalo, Peregrina, Jesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639051/
https://www.ncbi.nlm.nih.gov/pubmed/36179039
http://dx.doi.org/10.1021/acs.joc.2c01774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639051/
https://www.ncbi.nlm.nih.gov/pubmed/36179039
http://dx.doi.org/10.1021/acs.joc.2c01774

Ejemplares similares