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Synthesis of Bicyclic Hemiacetals Catalyzed by Unnatural Densely Substituted γ-Dipeptides

[Image: see text] The asymmetric synthesis of bicyclic highly substituted tetrahydropyrans is described. The reaction is catalyzed by unnatural γ-dipeptides based on densely substituted l- and d-proline derivatives. This organocatalytic one-pot reaction takes place among a ketone, a nitroalkene, and...

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Detalles Bibliográficos
Autores principales: Agirre, Maddalen, Bello, Tamara, Zhou, Jinxiu, Retamosa, María de Gracia, Cossío, Fernando P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639056/
https://www.ncbi.nlm.nih.gov/pubmed/36178434
http://dx.doi.org/10.1021/acs.joc.2c01230