Cargando…

Synthesis of Bicyclic Hemiacetals Catalyzed by Unnatural Densely Substituted γ-Dipeptides

[Image: see text] The asymmetric synthesis of bicyclic highly substituted tetrahydropyrans is described. The reaction is catalyzed by unnatural γ-dipeptides based on densely substituted l- and d-proline derivatives. This organocatalytic one-pot reaction takes place among a ketone, a nitroalkene, and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Agirre, Maddalen, Bello, Tamara, Zhou, Jinxiu, Retamosa, María de Gracia, Cossío, Fernando P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639056/ https://www.ncbi.nlm.nih.gov/pubmed/36178434 http://dx.doi.org/10.1021/acs.joc.2c01230

Ejemplares similares

Additive and Emergent Catalytic Properties of Dimeric Unnatural Amino Acid Derivatives: Aldol and Conjugate Additions
por: de Gracia Retamosa, María, et al.
Publicado: (2021)

Re(2)O(7)-catalyzed reaction of hemiacetals and aldehydes with O-, S-, and C-nucleophiles
por: Sittiwong, Wantanee, et al.
Publicado: (2013)

Stereoselective Synthesis of Densely Substituted Pyrrolidines via a [3 + 2] Cycloaddition Reaction between Chiral N-tert-Butanesulfinylazadienes and Azomethine Ylides
por: Blanco-López, Ester, et al.
Publicado: (2023)

AuCl(3)-Catalyzed Hemiacetal Activation for the Stereoselective Synthesis of 2-Deoxy Trehalose Derivatives
por: Jeanneret, Robin, et al.
Publicado: (2022)

Facile Access to Unnatural Dipeptide-Alcohols Based on cis-2,5-Disubstituted Pyrrolidines
por: Jia, Yan-Yan, et al.
Publicado: (2015)

Enantioselective [3 + 2] annulation of α-substituted allenoates with β,γ-unsaturated N-sulfonylimines catalyzed by a bifunctional dipeptide phosphine
por: Ni, Huanzhen, et al.
Publicado: (2016)

Unusual hemiacetal structure derived from Salvinorin A
por: Carvalho, Paulo, et al.
Publicado: (2008)

Formaldehyde Hemiacetal Sampling, Recovery, and Quantification from Electronic Cigarette Aerosols
por: Salamanca, James C., et al.
Publicado: (2017)

Switching DNA-binding specificity by unnatural amino acid substitution
por: Maiti, Atanu, et al.
Publicado: (2005)

Pd‐Catalyzed Asymmetric N‐Allylation of Amino Acid Esters with Exceptional Levels of Catalyst Control: Stereo‐Divergent Synthesis of ProM‐15 and Related Bicyclic Dipeptide Mimetics
por: Dohmen, Stephan, et al.
Publicado: (2020)

Appel-reagent-mediated transformation of glycosyl hemiacetal derivatives into thioglycosides and glycosyl thiols
por: Ghosh, Tamashree, et al.
Publicado: (2013)

Triacetin Enhances Levels of Acrolein, Formaldehyde Hemiacetals, and Acetaldehyde in Electronic Cigarette Aerosols
por: Vreeke, Shawna, et al.
Publicado: (2018)

Rh-Catalyzed Hydroformylation-Initiated Bicyclization: Construction of Azabicyclic Systems
por: Chiou, Wen-Hua, et al.
Publicado: (2020)

Transition-metal-catalyzed domino reactions of strained bicyclic alkenes
por: Pounder, Austin, et al.
Publicado: (2023)

Stereoselective β-mannosylations and β-rhamnosylations from glycosyl hemiacetals mediated by lithium iodide
por: Pongener, Imlirenla, et al.
Publicado: (2021)

γ-Alumina Nanoparticle Catalyzed Efficient Synthesis of Highly Substituted Imidazoles
por: Palakshi Reddy, Bandapalli, et al.
Publicado: (2015)

Unnatural causes /
por: James, P. D.
Publicado: (1981)

Unnatural Death
Publicado: (1899)

Stretchable, recyclable thermosets via photopolymerization and 3D printing of hemiacetal ester-based resins
por: Wu, You-Chi Mason, et al.
Publicado: (2023)

Molecular Mechanism Underlying the Action of Substituted Pro-Gly Dipeptide Noopept
por: Vakhitova, Y. V., et al.
Publicado: (2016)

Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin
por: Cleary, Jennifer A., et al.
Publicado: (2014)

Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase
por: Kudo, Kei, et al.
Publicado: (2021)

The unnatural nature of science
por: Wolpert, Lewis
Publicado: (1992)

Nickel-Catalyzed Amidoalkylation Reaction of γ-Hydroxy Lactams: An Access to 3-Substituted Isoindolinones†
por: Zhang, Shuo, et al.
Publicado: (2019)

Cascade N-Alkylation/Hemiacetalization for Facile Construction of the Spiroketal Skeleton of Acortatarin Alkaloids with Therapeutic Potentiality in Diabetic Nephropathy
por: Cao, Pei, et al.
Publicado: (2014)

Formation of Breslow Intermediates from N‐Heterocyclic Carbenes and Aldehydes Involves Autocatalysis by the Breslow Intermediate, and a Hemiacetal
por: Wessels, Alina, et al.
Publicado: (2022)

Direct Access to Unnatural Cyclobutane α-Amino Acids through Visible Light Catalyzed [2+2]-Cycloaddition
por: Stinglhamer, Martin, et al.
Publicado: (2022)

D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics
por: Lu, Jianguang, et al.
Publicado: (2020)

Phosphine-catalyzed enantioselective [3 + 2] cycloadditions of γ-substituted allenoates with β-perfluoroalkyl enones
por: Zhou, Wei, et al.
Publicado: (2017)

Phosphine-catalyzed divergent domino processes between γ-substituted allenoates and carbonyl-activated alkenes
por: Wu, Mingyue, et al.
Publicado: (2022)

Dipeptides of S-Substituted Dehydrocysteine as Artzyme Building Blocks: Synthesis, Complexing Abilities and Antiproliferative Properties †
por: Lenartowicz, Paweł, et al.
Publicado: (2021)

Higgs Mass and Unnatural Supersymmetry
por: Bagnaschi, Emanuele, et al.
Publicado: (2014)

Duality and unnatural-party trajectories
por: Dass, G V, et al.
Publicado: (1970)

Two Unnatural Cases of Labour
por: Hume, Thomas
Publicado: (1883)

A Case of Unnatural Labor
por: Ram, Doulat
Publicado: (1886)

A Case of Unnatural Labour
por: Singh, Charu
Publicado: (1886)

The Natural and Unnatural Feeding of the Infant
por: Findlay, Leonard
Publicado: (1910)

Extraordinary effects of unnatural pairings
por: Villarino, Alejandro, et al.
Publicado: (2017)

Rutin alleviated acrolein-induced cytotoxicity in Caco-2 and GES-1 cells by forming a cyclic hemiacetal product
por: Chen, Peifang, et al.
Publicado: (2022)

Fragmentation of Bicyclic γ-Silyloxy-β-hydroxy-α-diazolactones as an Approach to Ynolides
por: Bayir, Ali, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9p8en1b7miti7kptv6no40p0u1