Intravenous administration of viral vectors expressing prostate cancer antigens enhances the magnitude and functionality of CD8+ T cell responses

BACKGROUND: The use of immunotherapeutic vaccination in prostate cancer is a promising approach that likely requires the induction of functional, cytotoxic T cells. The experimental approach described here uses a well-studied adenovirus-poxvirus heterologous prime-boost regimen, in which the vectors...

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Detalles Bibliográficos
Autores principales: Vardeu, Antonella, Davis, Charlotte, McDonald, Ian, Stahlberg, Guilherme, Thapa, Barsha, Piotrowska, Kinga, Marshall, Margaret A, Evans, Thomas, Wheeler, Vicky, Sebastian, Sarah, Anderson, Katie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639133/
https://www.ncbi.nlm.nih.gov/pubmed/36323434
http://dx.doi.org/10.1136/jitc-2022-005398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639133/
https://www.ncbi.nlm.nih.gov/pubmed/36323434
http://dx.doi.org/10.1136/jitc-2022-005398

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