Pharmacokinetics of hydroxychloroquine in paediatric lupus: data from a novel, direct-to-family clinical trial

OBJECTIVE: Determine the pharmacokinetics (PK) and exposure–response of hydroxychloroquine (HCQ) and desethylhydroxychloroquine (DHCQ) in paediatric SLE (pSLE). METHODS: We conducted an exploratory phase 2, direct-to-family trial. Children enrolled in the Childhood Arthritis and Rheumatology Researc...

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Detalles Bibliográficos
Autores principales: Balevic, Stephen J, Randell, Rachel, Weiner, Daniel, Beard, Claire, Schanberg, Laura Eve, Hornik, Christoph P, Cohen-Wolkowiez, Michael, Gonzalez, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Childhood Lupus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639143/
https://www.ncbi.nlm.nih.gov/pubmed/36328395
http://dx.doi.org/10.1136/lupus-2022-000811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639143/
https://www.ncbi.nlm.nih.gov/pubmed/36328395
http://dx.doi.org/10.1136/lupus-2022-000811

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