Identification of natural product 3, 5-diiodotyrosine as APOBEC3B inhibitor to prevent somatic mutation accumulation and cancer progression

BACKGROUND: The development of cancer is largely dependent on the accumulation of somatic mutations, indicating the potential to develop cancer chemoprevention agents targeting mutation drivers. However, ideal cancer chemoprevention agents that can effectively inhibit the mutation drivers have not b...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Chunxia, Sui, Xinghua, Ning, Haoming, Sun, Yixuan, Du, Jiangfeng, Chen, Xiaotong, Zhou, Xiuman, Chen, Guanyu, Shen, Wenhui, Pang, Liwei, Zhou, Xiaowen, Shi, Ranran, Li, Wanqiong, Wang, Hongfei, Zhao, Wenshan, Zhai, Wenjie, Qi, Yuanming, Wu, Yahong, Gao, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639148/
https://www.ncbi.nlm.nih.gov/pubmed/36323433
http://dx.doi.org/10.1136/jitc-2022-005503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639148/
https://www.ncbi.nlm.nih.gov/pubmed/36323433
http://dx.doi.org/10.1136/jitc-2022-005503

Ejemplares similares