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Isotope-dilution LC-MS/MS analysis of the elastin crosslinkers desmosine and isodesmosine in acute cerebral stroke patients

Utilizing chemically synthesized an isotopically labeled internal standard, isodesmosine-(13)C(3),(15)N(1), an isotope-dilution LC-MS/MS method was established. Concentrations of desmosine and isodesmosine in plasma of acute cerebral stroke patients and healthy controls were determined. The concentr...

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Detalles Bibliográficos
Autores principales: Mikagi, Ayame, Tashiro, Ryosuke, Inoue, Tomoo, Anzawa, Riki, Imura, Akiho, Tanigawa, Takahiro, Ishida, Tomohisa, Inoue, Takashi, Niizuma, Kuniyasu, Tominaga, Teiji, Usuki, Toyonobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639221/
https://www.ncbi.nlm.nih.gov/pubmed/36380946
http://dx.doi.org/10.1039/d2ra06009d