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The LXRB-SREBP1 network regulates lipogenic homeostasis by controlling the synthesis of polyunsaturated fatty acids in goat mammary epithelial cells

BACKGROUND: In rodents, research has revealed a role of liver X receptors (LXR) in controlling lipid homeostasis and regulating the synthesis of polyunsaturated fatty acids (PUFA). Recent data suggest that LXRB is the predominant LXR subtype in ruminant mammary cells, but its role in lipid metabolis...

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Detalles Bibliográficos
Autores principales: Zhang, Wenying, Zhang, Changhui, Luo, Jun, Xu, Huifen, Liu, Jianxin, Loor, Juan J., Shi, Hengbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639257/
https://www.ncbi.nlm.nih.gov/pubmed/36336695
http://dx.doi.org/10.1186/s40104-022-00774-4