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Structural and energetic analyses of SARS-CoV-2 N-terminal domain characterise sugar binding pockets and suggest putative impacts of variants on COVID-19 transmission

Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is an ongoing pandemic that causes significant health/socioeconomic burden. Variants of concern (VOCs) have emerged affecting transmissibility, disease severity and re-infection risk. Studies suggest that the - N-terminal domain (NTD) of the s...

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Detalles Bibliográficos
Autores principales: Lam, Su Datt, Waman, Vaishali P., Fraternali, Franca, Orengo, Christine, Lees, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639386/
https://www.ncbi.nlm.nih.gov/pubmed/36408455
http://dx.doi.org/10.1016/j.csbj.2022.11.004