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Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death

Although macroautophagy deficits are implicated across adult-onset neurodegenerative diseases, we understand little about how the discrete, highly evolved cell types of the central nervous system use macroautophagy to maintain homeostasis. One such cell type is the oligodendrocyte, whose myelin shea...

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Detalles Bibliográficos
Autores principales: Aber, Etan R., Griffey, Christopher J., Davies, Tim, Li, Alice M., Yang, Young Joo, Croce, Katherine R., Goldman, James E., Grutzendler, Jaime, Canman, Julie C., Yamamoto, Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639605/
https://www.ncbi.nlm.nih.gov/pubmed/36261002
http://dx.doi.org/10.1016/j.celrep.2022.111480