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Cancer immunotherapy strategies that target the cGAS-STING pathway

Activation of the cGAS-STING pathway by cytoplasmic DNA induces the production of Type-1 interferons. Recent advances in research suggest that the cGAS-STING pathway is involved in different parts of the cancer-immunity cycle (CIC) to promote or suppress antitumor immune responses. Combination thera...

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Detalles Bibliográficos
Autores principales: Tian, Zhuoying, Zeng, Yue, Peng, Yurong, Liu, Junqi, Wu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639746/
https://www.ncbi.nlm.nih.gov/pubmed/36353640
http://dx.doi.org/10.3389/fimmu.2022.996663