Cargando…

Cancer immunotherapy strategies that target the cGAS-STING pathway

Activation of the cGAS-STING pathway by cytoplasmic DNA induces the production of Type-1 interferons. Recent advances in research suggest that the cGAS-STING pathway is involved in different parts of the cancer-immunity cycle (CIC) to promote or suppress antitumor immune responses. Combination thera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Zhuoying, Zeng, Yue, Peng, Yurong, Liu, Junqi, Wu, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639746/ https://www.ncbi.nlm.nih.gov/pubmed/36353640 http://dx.doi.org/10.3389/fimmu.2022.996663

Ejemplares similares

The cGAS-STING Pathway: A Promising Immunotherapy Target
por: Ou, Liang, et al.
Publicado: (2021)

The cGAS-STING Pathway: Novel Perspectives in Liver Diseases
por: Xu, Dongwei, et al.
Publicado: (2021)

The cGAS/STING Pathway: A Novel Target for Cancer Therapy
por: Gan, Yu, et al.
Publicado: (2022)

cGAS-STING Pathway as the Target of Immunotherapy for Lung Cancer
por: Dan, Qinfu, et al.
Publicado: (2023)

The cGAS-STING Pathway in Hematopoiesis and Its Physiopathological Significance
por: Liao, Weinian, et al.
Publicado: (2020)

The Function of cGAS-STING Pathway in Treatment of Pancreatic Cancer
por: Mohseni, Ghazal, et al.
Publicado: (2021)

The cGAS-STING Pathway in Bacterial Infection and Bacterial Immunity
por: Liu, Nanxin, et al.
Publicado: (2022)

Dysregulation of the cGAS-STING Pathway in Monogenic Autoinflammation and Lupus
por: Wobma, Holly, et al.
Publicado: (2022)

cGAS-STING signaling pathway in intestinal homeostasis and diseases
por: Yang, Yuchen, et al.
Publicado: (2023)

cGAS-STING, an important pathway in cancer immunotherapy
por: Jiang, Minlin, et al.
Publicado: (2020)

Radiation-Induced Immunity and Toxicities: The Versatility of the cGAS-STING Pathway
por: Constanzo, Julie, et al.
Publicado: (2021)

Insights on the cGAS-STING Signaling Pathway During Herpesvirus Infections
por: Deng, Lishuang, et al.
Publicado: (2022)

Crosstalk between cGAS-STING pathway and autophagy in cancer immunity
por: Lu, Qijun, et al.
Publicado: (2023)

cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging
por: Schmitz, Carine Raquel Richter, et al.
Publicado: (2023)

cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE
por: Motwani, Mona, et al.
Publicado: (2021)

The Alternatively Spliced Isoforms of Key Molecules in the cGAS-STING Signaling Pathway
por: Liang, Jiaqian, et al.
Publicado: (2021)

Can the cGAS-STING Pathway Play a Role in the Dry Eye?
por: Ouyang, Weijie, et al.
Publicado: (2022)

Corrigendum: Crosstalk between cGAS-STING pathway and autophagy in cancer immunity
por: Lu, Qijun, et al.
Publicado: (2023)

Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy
por: Zhang, Min, et al.
Publicado: (2022)

Function and regulation of cGAS-STING signaling in infectious diseases
por: Du, Yang, et al.
Publicado: (2023)

Updated roles of cGAS-STING signaling in autoimmune diseases
por: Liu, Ya, et al.
Publicado: (2023)

Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy
por: Li, Anping, et al.
Publicado: (2019)

cGAS–STING pathway in ischemia-reperfusion injury: a potential target to improve transplantation outcomes
por: Chen, Zijian, et al.
Publicado: (2023)

Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy
por: Podojil, Joseph R., et al.
Publicado: (2022)

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response
por: Wan, Dongshan, et al.
Publicado: (2020)

Advances in cGAS-STING Signaling Pathway and Diseases
por: Yang, Yuting, et al.
Publicado: (2022)

The role of cGAS-STING signaling in pulmonary fibrosis and its therapeutic potential
por: Zhang, Jing, et al.
Publicado: (2023)

Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis
por: Xia, Nengwen, et al.
Publicado: (2022)

The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability
por: Hong, Christy, et al.
Publicado: (2019)

cGAS-STING pathway in cancer biotherapy
por: Wang, Yang, et al.
Publicado: (2020)

The cGas–Sting Signaling Pathway Is Required for the Innate Immune Response Against Ectromelia Virus
por: Cheng, Wen-Yu, et al.
Publicado: (2018)

The battle between the innate immune cGAS-STING signaling pathway and human herpesvirus infection
por: Jin, Ximing, et al.
Publicado: (2023)

Novel insight into cGAS-STING pathway in ischemic stroke: from pre- to post-disease
por: Ma, Xiaoqi, et al.
Publicado: (2023)

cGAS-STING Pathway Performance in the Vulnerable Atherosclerotic Plaque
por: Wan, Xueqi, et al.
Publicado: (2022)

Pharmacological Activation of cGAS for Cancer Immunotherapy
por: Garland, Kyle M., et al.
Publicado: (2021)

Grouper cGAS is a negative regulator of STING-mediated interferon response
por: Zhang, Luhao, et al.
Publicado: (2023)

Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
por: Fischer, Katrin, et al.
Publicado: (2020)

Role of the cGAS/STING pathway in the control of Brucella abortus infection acquired through the respiratory route
por: Alonso Paiva, Iván M., et al.
Publicado: (2023)

Therapeutic Development by Targeting the cGAS-STING Pathway in Autoimmune Disease and Cancer
por: Li, Qiumei, et al.
Publicado: (2021)

African Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING
por: Zheng, Wanglong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_aah5l0rjeruvv5u0btn8ij0a7f