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Effect of sulfasalazine on endothelium-dependent vascular response by the activation of Nrf2 signalling pathway

Background: Diabetes mellitus leads to endothelial dysfunction and accumulation of oxygen radicals. Sulfasalazine-induced Nrf2 activation reduces oxidative stress in vessels. Thus, in the present study, we investigated the effects of sulfasalazine on endothelial dysfunction induced by high glucose....

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Detalles Bibliográficos
Autores principales: Sonmez, Muhammed Ikbal, Shahzadi, Andleeb, Kose, Cagla, Sonmez, Haktan, Ozyazgan, Sibel, Akkan, Ahmet Gokhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639785/
https://www.ncbi.nlm.nih.gov/pubmed/36353481
http://dx.doi.org/10.3389/fphar.2022.979300