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The OPRM1 gene and interactions with the 5-HT1a gene regulate conditioned pain modulation in fibromyalgia patients and healthy controls

Fibromyalgia (FM) patients have dysfunctional endogenous pain modulation, where opioid and serotonergic signaling is implicated. The aim of this study was to investigate whether genetic variants in the genes coding for major structures in the opioid and serotonergic systems can affect pain modulatio...

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Detalles Bibliográficos
Autores principales: Tour, Jeanette, Sandström, Angelica, Kadetoff, Diana, Schalling, Martin, Kosek, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639841/
https://www.ncbi.nlm.nih.gov/pubmed/36342939
http://dx.doi.org/10.1371/journal.pone.0277427