Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation

The WHO classifies t(6;9)-positive acute myeloid leukemia (AML) as a subgroup of high-risk AML because of its clinical and biological peculiarities, such as young age and therapy resistance. t(6;9) encodes the DEK/NUP214 fusion oncoprotein that targets only a small subpopulation of bone marrow proge...

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Detalles Bibliográficos
Autores principales: Chiriches, Claudia, Nicolaisen, Nathalie, Wieske, Maria, Elhaddad, Heba, Mehmetbeyoglu, Ecmel, Alvares, Caroline, Becher, Dörte, Hole, Paul, Ottmann, Oliver Gerhard, Ruthardt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639852/
https://www.ncbi.nlm.nih.gov/pubmed/36288392
http://dx.doi.org/10.1371/journal.pgen.1010463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639852/
https://www.ncbi.nlm.nih.gov/pubmed/36288392
http://dx.doi.org/10.1371/journal.pgen.1010463

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