Novel ciprofloxacin and norfloxacin-tetrazole hybrids as potential antibacterial and antiviral agents: Targeting S. aureus topoisomerase and SARS-CoV-2-MPro

This study was designed to synthesize hybridizing molecules from ciprofloxacin and norfloxacin by enhancing their biological activity with tetrazoles. The synthesized compounds were investigated in the interaction with the target enzyme of fluoroquinolones (DNA gyrase) and COVID-19 main protease usi...

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Detalles Bibliográficos
Autores principales: Cardoso-Ortiz, Jaime, Leyva-Ramos, Socorro, Baines, Kim M., Gómez-Durán, Cesar Fernando Azael, Hernández-López, Hiram, Palacios-Can, Francisco José, Valcarcel-Gamiño, José Antonio, Leyva-Peralta, Mario Alberto, Razo-Hernández, Rodrigo Said
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640164/
https://www.ncbi.nlm.nih.gov/pubmed/36406777
http://dx.doi.org/10.1016/j.molstruc.2022.134507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640164/
https://www.ncbi.nlm.nih.gov/pubmed/36406777
http://dx.doi.org/10.1016/j.molstruc.2022.134507

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