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Computational model of the full-length TSH receptor

(GPCR)The receptor for TSH receptor (TSHR), a G protein coupled receptor (GPCR), is of particular interest as the primary antigen in autoimmune hyperthyroidism (Graves’ disease) caused by stimulating TSHR antibodies. To date, only one domain of the extracellular region of the TSHR has been crystalli...

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Detalles Bibliográficos
Autores principales: Mezei, Mihaly, Latif, Rauf, Davies, Terry F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640187/
https://www.ncbi.nlm.nih.gov/pubmed/36305581
http://dx.doi.org/10.7554/eLife.81415