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Augmin prevents merotelic attachments by promoting proper arrangement of bridging and kinetochore fibers

The human mitotic spindle is made of microtubules nucleated at centrosomes, at kinetochores, and from pre-existing microtubules by the augmin complex. However, it is unknown how the augmin-mediated nucleation affects distinct microtubule classes and thereby mitotic fidelity. Here, we use superresolu...

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Detalles Bibliográficos
Autores principales: Štimac, Valentina, Koprivec, Isabella, Manenica, Martina, Simunić, Juraj, Tolić, Iva M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640188/
https://www.ncbi.nlm.nih.gov/pubmed/36269126
http://dx.doi.org/10.7554/eLife.83287