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Full opening of helix bundle crossing does not lead to NaK channel activation

A critical part of ion channel function is the ability to open and close in response to stimuli and thus conduct ions in a regulated fashion. While x-ray diffraction studies of ion channels suggested a general steric gating mechanism located at the helix bundle crossing (HBC), recent functional stud...

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Detalles Bibliográficos
Autores principales: Kurauskas, Vilius, Tonelli, Marco, Henzler-Wildman, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640265/
https://www.ncbi.nlm.nih.gov/pubmed/36326620
http://dx.doi.org/10.1085/jgp.202213196