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Full opening of helix bundle crossing does not lead to NaK channel activation
A critical part of ion channel function is the ability to open and close in response to stimuli and thus conduct ions in a regulated fashion. While x-ray diffraction studies of ion channels suggested a general steric gating mechanism located at the helix bundle crossing (HBC), recent functional stud...
Autores principales: | Kurauskas, Vilius, Tonelli, Marco, Henzler-Wildman, Katherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640265/ https://www.ncbi.nlm.nih.gov/pubmed/36326620 http://dx.doi.org/10.1085/jgp.202213196 |
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