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Single-cell RNA-sequencing analysis of aortic valve interstitial cells demonstrates the regulation of integrin signaling by nitric oxide

Calcific aortic valve disease (CAVD) is an increasingly prevalent condition among the elderly population that is associated with significant morbidity and mortality. Insufficient understanding of the underlying disease mechanisms has hindered the development of pharmacologic therapies for CAVD. Rece...

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Detalles Bibliográficos
Autores principales: Majumdar, Uddalak, Choudhury, Talita Z., Manivannan, Sathiyanarayanan, Ueyama, Yukie, Basu, Madhumita, Garg, Vidu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640371/
https://www.ncbi.nlm.nih.gov/pubmed/36386365
http://dx.doi.org/10.3389/fcvm.2022.742850