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Single-cell RNA-sequencing analysis of aortic valve interstitial cells demonstrates the regulation of integrin signaling by nitric oxide
Calcific aortic valve disease (CAVD) is an increasingly prevalent condition among the elderly population that is associated with significant morbidity and mortality. Insufficient understanding of the underlying disease mechanisms has hindered the development of pharmacologic therapies for CAVD. Rece...
Autores principales: | Majumdar, Uddalak, Choudhury, Talita Z., Manivannan, Sathiyanarayanan, Ueyama, Yukie, Basu, Madhumita, Garg, Vidu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640371/ https://www.ncbi.nlm.nih.gov/pubmed/36386365 http://dx.doi.org/10.3389/fcvm.2022.742850 |
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