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Roles of effective stabilizers in improving oral bioavailability of naringenin nanocrystals: Maintenance of supersaturation generated upon dissolution by inhibition of drug dimerization

Nanocrystals (NCs), a colloidal dispersion system formulated with stabilizers, have attracted widespread interest due to their ability to effectively improve the oral bioavailability of poorly water-soluble drugs. The stabilizer plays a key role because it can affect the physical stability and even...

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Detalles Bibliográficos
Autores principales: Zhang, Guangshuai, Guan, Haishan, Li, Jianfeng, Li, Mo, Sui, Xiaofan, Tian, Baocheng, Dong, Huiming, Liu, Bingyang, He, Zhonggui, Li, Ning, Zhao, Mingming, Fu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640469/
https://www.ncbi.nlm.nih.gov/pubmed/36382308
http://dx.doi.org/10.1016/j.ajps.2022.09.001