Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models

Asthma is a common respiratory disease associated with airway hyperresponsiveness (AHR), airway inflammation and mast cell (MC) accumulation in the lung. Monensin, an ionophoric antibiotic, has been shown to induce apoptosis of human MCs. The aim of this study was to define the effect of monensin on...

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Detalles Bibliográficos
Autores principales: Liu, Jielu, Nie, Mu, Dong, Caijuan, Säfholm, Jesper, Pejler, Gunnar, Nilsson, Gunnar, Adner, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640546/
https://www.ncbi.nlm.nih.gov/pubmed/36344588
http://dx.doi.org/10.1038/s41598-022-23486-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640546/
https://www.ncbi.nlm.nih.gov/pubmed/36344588
http://dx.doi.org/10.1038/s41598-022-23486-1

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