Forecasting individual progression trajectories in Huntington disease enables more powered clinical trials

Variability in neurodegenerative disease progression poses great challenges for the evaluation of potential treatments. Identifying the persons who will experience significant progression in the short term is key for the implementation of trials with smaller sample sizes. We apply here disease cours...

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Detalles Bibliográficos
Autores principales: Koval, Igor, Dighiero-Brecht, Thomas, Tobin, Allan J., Tabrizi, Sarah J., Scahill, Rachael I., Tezenas du Montcel, Sophie, Durrleman, Stanley, Durr, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640581/
https://www.ncbi.nlm.nih.gov/pubmed/36344508
http://dx.doi.org/10.1038/s41598-022-18848-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640581/
https://www.ncbi.nlm.nih.gov/pubmed/36344508
http://dx.doi.org/10.1038/s41598-022-18848-8

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