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Forecasting individual progression trajectories in Huntington disease enables more powered clinical trials
Variability in neurodegenerative disease progression poses great challenges for the evaluation of potential treatments. Identifying the persons who will experience significant progression in the short term is key for the implementation of trials with smaller sample sizes. We apply here disease cours...
Autores principales: | Koval, Igor, Dighiero-Brecht, Thomas, Tobin, Allan J., Tabrizi, Sarah J., Scahill, Rachael I., Tezenas du Montcel, Sophie, Durrleman, Stanley, Durr, Alexandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640581/ https://www.ncbi.nlm.nih.gov/pubmed/36344508 http://dx.doi.org/10.1038/s41598-022-18848-8 |
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