Cargando…

Computational simulation and target prediction studies of solubility optimization of decitabine through supercritical solvent

Computational analysis of drug solubility was carried out using machine learning approach. The solubility of Decitabine as model drug in supercritical CO(2) was studied as function of pressure and temperature to assess the feasibility of that for production of nanomedicine to enhance the solubility....

Descripción completa

Detalles Bibliográficos
Autores principales: Alshahrani, Saad M., Almutairy, Bjad K., Alfadhel, Munerah M., Belal, Amany, Abourehab, Mohammed A. S., Saqr, Ahmed Al., Alshetaili, Abdullah S., Venkatesan, Kumar, Alsubaiyel, Amal M., Pishnamazi, Mahboubeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640585/
https://www.ncbi.nlm.nih.gov/pubmed/36344531
http://dx.doi.org/10.1038/s41598-022-21233-0