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Computational simulation and target prediction studies of solubility optimization of decitabine through supercritical solvent
Computational analysis of drug solubility was carried out using machine learning approach. The solubility of Decitabine as model drug in supercritical CO(2) was studied as function of pressure and temperature to assess the feasibility of that for production of nanomedicine to enhance the solubility....
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640585/ https://www.ncbi.nlm.nih.gov/pubmed/36344531 http://dx.doi.org/10.1038/s41598-022-21233-0 |