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Optimization of 3D-aggregated spheroid model (3D-ASM) for selecting high efficacy drugs

Various three-dimensional (3D) cell culture methods have been developed to implement tumor models similar to in vivo. However, the conventional 3D cell culture method has limitations such as difficulty in using an extracellular matrix (ECM), low experimental reproducibility, complex 3D cell culture...

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Detalles Bibliográficos
Autores principales: Lee, Sang-Yun, Hwang, Hyun Ju, Lee, Dong Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640609/
https://www.ncbi.nlm.nih.gov/pubmed/36344810
http://dx.doi.org/10.1038/s41598-022-23474-5