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Optimization of 3D-aggregated spheroid model (3D-ASM) for selecting high efficacy drugs
Various three-dimensional (3D) cell culture methods have been developed to implement tumor models similar to in vivo. However, the conventional 3D cell culture method has limitations such as difficulty in using an extracellular matrix (ECM), low experimental reproducibility, complex 3D cell culture...
Autores principales: | Lee, Sang-Yun, Hwang, Hyun Ju, Lee, Dong Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640609/ https://www.ncbi.nlm.nih.gov/pubmed/36344810 http://dx.doi.org/10.1038/s41598-022-23474-5 |
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