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CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses

Alterations in cellular metabolism underpin macrophage activation, yet little is known regarding how key immunological molecules regulate metabolic programs in macrophages. Here we uncover a function for the antigen presenting molecule CD1d in the control of lipid metabolism. We show that CD1d-defic...

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Detalles Bibliográficos
Autores principales: Brailey, Phillip M., Evans, Lauren, López-Rodríguez, Juan Carlos, Sinadinos, Anthony, Tyrrel, Victoria, Kelly, Gavin, O’Donnell, Valerie, Ghazal, Peter, John, Susan, Barral, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640663/
https://www.ncbi.nlm.nih.gov/pubmed/36344546
http://dx.doi.org/10.1038/s41467-022-34532-x