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Neuroprotective action of α-Klotho against LPS-activated glia conditioned medium in primary neuronal culture

The α-Klotho is an anti-aging protein that, when overexpressed, extends the life span in humans and mice. It has an anti-inflammatory and protective action on renal cells by inhibiting NF-κB activation and production of inflammatory cytokines in response to TNF-α. Furthermore, studies have shown the...

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Detalles Bibliográficos
Autores principales: Nakao, Vinicius Wanatable, Mazucanti, Caio Henrique Yokowama, de Sá Lima, Larissa, de Mello, Paloma Segura, de Souza Port’s, Natacha Medeiros, Kinoshita, Paula Fernanda, Leite, Jacqueline Alves, Kawamoto, Elisa Mitiko, Scavone, Cristoforo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640694/
https://www.ncbi.nlm.nih.gov/pubmed/36344527
http://dx.doi.org/10.1038/s41598-022-21132-4