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PA-MSHA induces inflamed tumor microenvironment and sensitizes tumor to anti-PD-1 therapy

A low response rate to immune checkpoint inhibitor (ICI) therapy has impeded its clinical use. As reported previously, an inflamed tumor microenvironment (TME) was directly correlated with patients’ response to immune checkpoint blockade (ICB). Thus, restoring the cytotoxic effect of immune cells in...

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Detalles Bibliográficos
Autores principales: Huang, Min, He, Fang, Li, Dan, Xie, Ya-Jia, Jiang, Ze-Bo, Huang, Ju-Min, Zhao, Xiao-Ping, Nasim, Ali Adnan, Chen, Jun-Hui, Hou, Jin-Cai, Fan, Xian-Ming, Leung, Elaine Lai-Han, Fan, Xing-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640707/
https://www.ncbi.nlm.nih.gov/pubmed/36344505
http://dx.doi.org/10.1038/s41419-022-05368-6