A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice

Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate and adaptive immune system and act to inhibit their inflammatory activities, and 2) lung epithelial cells and GABA-R agonists/potentiato...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Jide, Dillion, Barbara J., Henley, Jill, Comai, Lucio, Kaufman, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640739/
https://www.ncbi.nlm.nih.gov/pubmed/36389819
http://dx.doi.org/10.3389/fimmu.2022.1007955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640739/
https://www.ncbi.nlm.nih.gov/pubmed/36389819
http://dx.doi.org/10.3389/fimmu.2022.1007955

Ejemplares similares