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A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice
Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate and adaptive immune system and act to inhibit their inflammatory activities, and 2) lung epithelial cells and GABA-R agonists/potentiato...
Autores principales: | Tian, Jide, Dillion, Barbara J., Henley, Jill, Comai, Lucio, Kaufman, Daniel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640739/ https://www.ncbi.nlm.nih.gov/pubmed/36389819 http://dx.doi.org/10.3389/fimmu.2022.1007955 |
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